Market Pulse
GlaxoSmithKline appoints Hal Barron as R&D boss, replacing Vallance
GlaxoSmithKline has appointed Hal Barron - currently president of research & development at Alphabet-funded Calico - as chief scientific officer and president of R&D, replacing Patrick Vallance.
Paul Haworth joins GetBusy as CFO
GetBusy announced on Wednesday that Paul Haworth has joined the company as chief financial officer, initially in a non-board position.
ReNeuron makes solid progress with hRPC trials
Cell-based therapeutics developer ReNeuron Group updated the market on Wednesday on its ongoing Phase I/II clinical trial of its hRPC cell therapy candidate for the blindness-causing disease retinitis pigmentosa.
US pre-open: Stocks seen muted after another record high for the Dow
US futures pointed to a muted open on Wall Street on Wednesday after the Dow notched another record closing high the day before.
Genedrive COO Allan Brown to leave
AIM-listed Genedrive has announced the departure of chief operating officer, Allan Brown, with immediate effect.
Europe midday: Stocks hold lower
European stocks are still trading slighty lower come midday in the wake of weaker-than-expected data on Chinese foreign trade.
Barclays stays at 'underweight' on Rolls Royce
Analysts at Barclays have hiked their target price for shares of Rolls Royce but take issue with the current 5% free cash flow yield the stock is trading on, telling clients the market is using a peak level to calculate the company's future cash flows as a reference.
Rio Tinto eyeing £4bn stake in Chilean lithium producer - reports
Rio Tinto is said to be mulling the acquisition of a $5bn (£3. 8bn) stake in a Chilean lithium producer as demand for the metal surges due to its use in electric car batteries.
Snoozebox appoints administrators
Snoozebox has appointed administrators after discussions with its primary lender failed to bear fruit.
Asia report: Markets mixed as investors struggle for direction
Asian markets finished mixed but little changed on Wednesday, with investors struggling for direction after a similarly mixed session on Wall Street overnight.
Snap plans major Snapchat redesign as losses widen, Tencent buys stake
Snapchat parent company Snap announced that it was working on an overhaul of the popular photo and video messaging application after it reported losses of more than $400m in its last trading quarter.
Wednesday broker round-up
AB Foods: Goldman Sachs downgrades to Neutral with a target price of 3400p.
Chinese export volumes cool in October amid holidays, EM slowdown
Both inbound and outbound trade from China cooled last month, but some economists are confident that any slowdown will be modest despite a loss of momentum in other emerging markets.
London midday: Stocks nudge lower as housebuilders weigh
London stocks had turned a little lower by midday on Wednesday amid weakness in the housebuilding sector following a trading statement from Persimmon.
Europe open: Stocks slip on weak Chinese trade data
European stocks are trading slighty lower in the wake of weaker-than-expected data on Chinese foreign trade.
Sky News future in doubt if Fox deal is blocked
Broadcaster Sky has said it would have to review the future of its Sky News operation if regulators were to block a proposed move for 21st Century Fox to purchase the 61% of the company it does not currently own.
Bacanora sizzles after German lithium license approved
Mexico-focussed lithium exploration and development company Bacanora Minerals was granted a mining licence for its Zinnwald project in south Saxony, Germany, making it just a few steps removed from having its second lithium mine in operation.
LA-108 drill programme exceeds expectations for Victoria Oil and Gas
London-based gas utility company Victoria Oil and Gas successfully reached target depth of 2,865m measured depth (MD) at well LA-108 at its Logbaba project in Cameroon, encountering a net pay of 84. 5m in the process.
Goldman downgrades AB Foods on sugar prices, slower Primark growth
Associated British Foods shares offer limited upside as profits will be dulled by lower European Union sugar prices, said Goldman Sachs as it downgraded its recommendation to 'neutral' from 'buy'.
Wetherspoon chairman attacks fellow bosses for Brexit 'misinformation'
JD Wetherspoon's chairman has accused bosses of other companies of spreading misinformation about the impact of Brexit as the pub chain reported higher first-quarter sales.