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Okyo aims to complete eye disease trials before June
Okyo Pharma Limited reported on Wednesday that its preclinical studies of non-opioid painkiller BAM8 are expected to complete within the second quarter of the year.
Barnier says delay of Article 50 is wrong priority
The UK should focus more on finding a consensual Brexit agreement than stopping a no-deal departure, the European's chief negotiator said on Wednesday.
McConnell again blocks Democrat attempt to re-open US govt
Senate majority leader Mitch McConnell on Wednesday blocked a bill proposed by the Democrats to reopen the US government for the fourth time.
US close: Dow closes 170 points higher despite ongoing government shutdown
US stocks carved out some gains on Wednesday, as traders shrugged off the previous day's losses despite lingering concerns about trade relations between the US and China.
US open: Stocks shrug off lingering concerns surrounding US-Sino relations
Wall Street trading began with some gains on Wednesday, as traders shrugged off the previous day's losses despite lingering concerns about trade relations between the US and China.
P&G up guidance following strong Q2
Consumer goods giant Procter & Gamble has upped its full-year guidance on the back of strong sales of products ranging from skin cream to fabric softener in its last trading quarter.
Europe close:Stocks slip on ongoing trade concerns
A bounce in European stocks petered out after a top Chinese official warned of the growing risks the international order was facing from populism and as crude oil futures retreated on talk of a still strong outlook for US shale oil.
Credit Bank of Moscow breaks into top five for corporate bond sales in Russia
Credit Bank of Moscow's corporate debt syndication team had a very busy 2018, breaking into the top five in a national ranking of lead sales arrangers.
Credit Suisse downgrades Centrica to 'neutral'
Analysts at Credit Suisse downgraded shares of energy and services outfit Centrica to 'neutral' on Wednesday, saying that they expected a rough time for the firm's share price throughout February.
Senate sets vote to break US government shutdown impasse
Senate leaders have agreed to hold votes this week on proposals that could lead to a reopening of the government and provide relief for 800,000 federal workers.
London close: Stocks slip on US-China trade concerns, strength in Sterling
London stocks finished in the red on Wednesday as concerns about trade tensions between the US and China and a downbeat assessment of the UK manufacturing sector weighed on sentiment.
Sector movers: Pound giveth and taketh away
Automobiles, construction groups and aerospace were the big fallers on Wednesday, while domestic focused sectors were on the up.
Broker tips: Centrica, Metro Bank, FTSE 100 'top ten' sells
Analysts at Credit Suisse downgraded energy and services outfit Centrica to 'neutral' on Wednesday, expecting a rough time for the firm's share price throughout February.
Harwood WM's assets leap after nine acquisitions
Harwood Wealth Management on Wednesday reported that a "strong" year of growth has seen a sharp rise in assets and the completion of nine acquisitions.
Metro Bank 'likely' to need new fundraising, analysts say
Metro Bank is now "increasingly likely" to go back to the City with its begging bowl, some analysts suggested after the lender's surprise trading update on Wednesday.
Block Energy launches two-well sidetracking programme
Block Energy rose on Wednesday after beginning sidetrack operations in the existing 16a wellbore at its West Rustavi field in the Republic of Georgia.
Crusader Resources warns of funding shortfall
Exploration and development outfit Crusader Resources warned investors on Wednesday that it continues to require additional immediate funding to continue operating.
Director dealings: Entertainment One founder disposes of significant stake
Entertainment One chief executive Darren Throop sold 1. 5m ordinary shares in the Toronto-based mass media outfit on Wednesday.
CMA gets celebs to agree to transparent social media ads
The UK competition watchdog has secured formal commitments from celebrities and social media 'influencers' to be transparent on their posts where they advertise products to their followers.
FTSE 100 movers: Burberry struts higher, Centrica hit by downgrade
London's FTSE 100 was down 0. 9% to 6,842. 93 in afternoon trade on Wednesday as sterling rallied amid indications that a no-deal Brexit was becoming less likely.